Here are some extracts of Neil DeGrasse’s recent opinion piece on the Huffington Post:
What is the essence of science?
Do whatever it takes to avoid fooling yourself into thinking something is true that is not, or that something is not true that is.
How do you “do” science?
Conduct experiments to test your hypothesis and allocate your confidence in proportion to the strength of your evidence. Since then, we would further learn not to claim knowledge of a newly discovered truth until multiple researchers, and ultimately the majority of researchers, obtain results consistent with one another.
How does it help you learn more about the world?
Science finds objective truths (can be verified anytime by anyone) regardless of whether you believe then or not.